Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

Author:

Zhu Rong1,Sinwel Doris12,Hasenhuetl Peter S.3,Saha Kusumika3,Kumar Vivek4,Zhang Peng4,Rankl Christian5,Holy Marion3,Sucic Sonja3,Kudlacek Oliver3,Karner Andreas16,Sandtner Walter3,Stockner Thomas3,Gruber Hermann J.1,Freissmuth Michael3,Newman Amy Hauck4,Sitte Harald H.3,Hinterdorfer Peter126

Affiliation:

1. Institute for Biophysics; Johannes Kepler University Linz; Gruberstrasse 40 4020 Linz Austria

2. Christian Doppler Laboratory for Nanoscopic Methods in Biophysics; Johannes Kepler University Linz; Gruberstrasse 40 4020 Linz Austria

3. Center of Physiology and Pharmacology; Medical University of Vienna; Waehringerstrasse 13a 1090 Vienna Austria

4. Medicinal Chemistry Section; Molecular Targets and Medications Discovery Branch; Intramural Research Program; National Institute on Drug Abuse; Baltimore MD 21224 USA

5. Keysight Technologies Austria GmbH; Mooslackengasse 17 1190 Vienna Austria

6. Center for Advanced Bioanalysis; Gruberstrasse 40 4020 Linz Austria

Funder

Austrian Science Fund

National Institute on Drug Abuse-Intramural Research Program

NIH

Publisher

Wiley

Subject

General Medicine

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