Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1-Reference-Cited by-同舟云学术

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Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1

Published:2016-10-10 Issue:45 Volume:128 Page:14191-14195
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

Fontanillo Miriam¹,Zemskov Ivan²,Häfner Maximilian²,Uhrig Ulrike³,Salvi Francesca¹,Simon Bernd⁴^ORCID,Wittmann Valentin²^ORCID,Köhn Maja¹^ORCID

Affiliation:

1. Genome Biology Unit; European Molecular Biology Laboratory; Meyerhofstrasse 1 69117 Heidelberg Germany

2. Department of Chemistry and Konstanz Research School Chemical Biology (KoRS-CB); University of Konstanz; Fach 709 78457 Konstanz Germany

3. Chemical Biology Core Facility; European Molecular Biology Laboratory; Meyerhofstrasse 1 69117 Heidelberg Germany

4. Structural and Computational Biology Unit; European Molecular Biology Laboratory; Meyerhofstrasse 1 69117 Heidelberg Germany

Publisher

Wiley

Subject

General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ange.201606449/fullpdf

Reference31 articles.

1. Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

2. Serine/Threonine Phosphatases: Mechanism through Structure

3. From Promiscuity to Precision: Protein Phosphatases Get a Makeover

4. Protein Ser/ Thr phosphatases - the ugly ducklings of cell signalling

5. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ultrasensitive photoelectrochemical detection of microcystin-LR based on hybridization chain reaction assisted exciton-plasmon interaction and enzymatic biocatalytic precipitation;Sensors and Actuators B: Chemical;2018-12

2. Directing the Heterologous Production of Specific Cyanobacterial Toxin Variants;ACS Chemical Biology;2017-06-07

3. Total Synthesis of Microcystin-LF and Derivatives Thereof;The Journal of Organic Chemistry;2017-03-27

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