Molecular Engineering‐Based Aptamer–Drug Conjugates with Accurate Tunability of Drug Ratios for Drug Combination Targeted Cancer Therapy

Author:

Zhou Fang1,Wang Peng1,Peng Yongbo1,Zhang Pengge1,Huang Qin1,Sun Weidi1,He Nongyue2,Fu Ting1,Zhao Zilong1,Fang Xiaohong3,Tan Weihong14ORCID

Affiliation:

1. Molecular Science and Biomedicine Laboratory (MBL) State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical Engineering College of Life Sciences Aptamer Engineering Center of Hunan Province Hunan University Changsha 410082 P. R. China

2. State Key Laboratory of Bioelectronics National Demonstration Center for Experimental Biomedical Engineering Education School of Biological Science and Medical Engineering Southeast University Nanjing 210096 P. R. China

3. Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China

4. Department of Chemistry, Department of Physiology and Functional Genomics Center for Research at Bio/Nano Interface UF Health Cancer Center UF Genetics Institute and McKnight Brain Institute University of Florida Gainesville FL 32611-7200 USA

Funder

National Natural Science Foundation of China

State Key Laboratory of Chemo/Biosensing and Chemometrics

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

General Medicine

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