A Scalable Total Synthesis of the Antitumor Agents Et‐743 and Lurbinectedin-Reference-Cited by-同舟云学术

A Scalable Total Synthesis of the Antitumor Agents Et‐743 and Lurbinectedin

Published:2019-02-14 Issue:12 Volume:131 Page:4012-4015
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angew. Chem.

Author:

He Weiming¹,Zhang Zhigao¹,Ma Dawei¹^ORCID

Affiliation:

1. Interdisciplinary Center on Biology and Chemistry & State Key Laboratory of Bioorganic & Natural Products ChemistryCenter for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of Sciences 345 Lingling Lu Shanghai 200032 China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.201900035

Reference39 articles.

1. For reviews see:

2. Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem

3. Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics

5. DNA Sequence- and Structure-Selective Alkylation of Guanine N2 in the DNA Minor Groove by Ecteinascidin 743, a Potent Antitumor Compound from the Caribbean Tunicate Ecteinascidia turbinata

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