Enzymatic C−H Oxidation-Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity

Author:

Li Jie1,Tang Xiaoyu1,Awakawa Takayoshi12,Moore Bradley S.13ORCID

Affiliation:

1. Center of Marine Biotechnology and Biomedicine; Scripps Institution of Oceanography; University of California at San Diego; 9500 Gilman Drive La Jolla CA 92093-0204 USA

2. Graduate School of Pharmaceutical Sciences; The University of Tokyo; 7-3-1 Hongo, Bunkyo-ku Tokyo 113-0033 Japan

3. Skaggs School of Pharmacy and Pharmaceutical Sciences; University of California at San Diego; 9500 Gilman Drive La Jolla CA 92093 USA

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

General Medicine

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