Rosbin, a synthetic small molecule, induces A549 cells apoptosis through a ROS-mediated pathway

Author:

Zhao Ting12,Jin Wenling2,Pan Hui2,Li Haizhou2,Zhao Yang3,Feng Yang2

Affiliation:

1. Faculty of Environmental Science and Engineering; Kunming University of Science and Technology; Kunming Yunnan 6505001 P.R. China

2. Faculty of Life Science and Technology; Kunming University of Science and Technology; Kunming Yunnan 650500 P.R. China

3. Institute of Plant Physiology and Ecology; Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences; Shanghai 20000 P.R. China

Funder

Kunming University of Science and Technology

The Personnel Training Project of Yunnan Province

Key Subject Project Foundation

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference24 articles.

1. Production of superoxide by human malignant melanoma cells;Bittinger;Melanoma Res,1998

2. Oxidative stress as a mediator of apoptosis;Buttke;Immunol Today,1994

3. Experimental therapeutics: targeting the redox Achilles heel of cancer;Cabello;Curr Opin Investig Drugs,2007

4. Oleananetriterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism;Deeb;Biochem Pharmacol,2010

5. Proliferation, cell cycle and apoptosis in cancer;Evan;Nature,2001

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