Alzheimer's disease, estrogens, and clinical trials: a case study in drug development for complex disorders
Author:
Publisher
Wiley
Subject
Drug Discovery
Reference313 articles.
1. Critical in Vivo Roles for Classical Estrogen Receptors in Rapid Estrogen Actions on Intracellular Signaling in Mouse Brain
2. -Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase
3. Palmitoylation-dependent Estrogen Receptor α Membrane Localization: Regulation by 17β-Estradiol
4. Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial
5. Different modes of hippocampal plasticity in response to estrogen in young and aged female rats
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1. Effects of Tibolone on the Central Nervous System: Clinical and Experimental Approaches;BioMed Research International;2017
2. A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease;Hormones and Behavior;2016-07
3. Mitochondrial Drugs Come of Age;Drug Development Research;2015-03
4. Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential;Drug Development Research;2009-02
5. 17α-estradiol: a less-feminizing estrogen;Drug Development Research;2008-06
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