Clearance of systemic hematologic tumors by venetoclax (Abt‐199) and navitoclax

Author:

Ackler Scott1,Oleksijew Anatol1,Chen Jun1,Chyla Brenda J.1,Clarin Jerry1,Foster Kelly1,McGonigal Thomas1,Mishra Sasmita1,Schlessinger Sally1,Smith Morey L.1,Tahir Stephen K.1,Leverson Joel D.1,Souers Andrew J.1,Boghaert Erwin R.1,Hickson Jonathan1

Affiliation:

1. AbbVie Inc. North Chicago Illinois

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference27 articles.

1. The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo

2. Navitoclax (ABT-263) and bendamustine ± rituximab induce enhanced killing of non-Hodgkin's lymphoma tumoursin vivo

3. Response: Microenvironment-dependent resistance to ABT-737 in chronic lymphocytic leukemia

4. Chronic Lymphocytic Leukemia

5. The Bcl‐2‐specific BH3‐mimetic ABT‐199 (GDC‐0199) is active and well‐tolerated in patients with relapsed non‐Hodgkin lymphoma: interim results of a phase I study;Davids MS;Blood (ASH Annual Meeting Abstracts),2012

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