Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model-Reference-Cited by-同舟云学术

Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model

Published:2023-07 Issue:3 Volume:13 Page:
ISSN:2045-8940
Container-title:Pulmonary Circulation
language:en
Short-container-title:Pulm. circ.

Author:

Sanada Takayuki J.¹²^ORCID,Hosomi Koji¹,Park Jonguk³,Naito Akira²,Sakao Seiichiro²,Tanabe Nobuhiro²⁴,Kunisawa Jun¹³⁵⁶⁷,Tatsumi Koichiro²,Suzuki Takuji²

Affiliation:

1. Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN) Osaka Japan

2. Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan

3. Artificial Intelligence Center for Health and Biomedical Research National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Osaka Japan

4. Department of Respirology Chibaken Saiseikai Narashino Hospital Narashino Japan

5. Graduate School of Pharmaceutical Sciences Osaka University Osaka Japan

6. Graduate School of Medicine Osaka University Osaka Japan

7. Graduate School of Dentistry Osaka University Osaka Japan

Abstract

AbstractThis study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pul2.12266

Reference20 articles.

1. Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

2. Pulmonary haemodynamics are correlated with intimal lesions in a rat model of severe PAH: attenuation of pulmonary vascular remodelling with ambrisentan;Takeuchi T;Histol Histopathol,2016

3. The Role and Mechanism of Gut Microbiota in Pulmonary Arterial Hypertension

4. Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

5. Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aplicações biotecnológicas e propriedades farmacológicas da goma guar com ênfase na atividade anticolinesterásica: uma prospecção científica e tecnológica;Caderno Pedagógico;2024-03-21

2. Dietary Regimens: Whole Grains and Multiple Sclerosis;Nutritional Neurosciences;2024