Acute opioid overdose in pediatric patients

Author:

Sandelich Stephen1ORCID,Hooley Gwen2,Hsu George3,Rose Emily4,Ruttan Tim5,Schwarz Evan S.6,Simon Erin7,Sulton Carmen8,Wall Jessica9,Dietrich Ann M10

Affiliation:

1. Department of Emergency Medicine Penn State College of Medicine Penn State Milton S. Hershey Medical Center Hershey Pennsylvania USA

2. Department of Emergency Medicine Children's Hospital of Los Angeles Los Angeles California USA

3. Department of Emergency Medicine Augusta University‐Medical College of Georgia Augusta Georgia USA

4. Department of Emergency Medicine Keck School of Medicine of the University of Southern California Los Angeles General Medical Center Los Angeles California USA

5. Department of Pediatrics Dell Medical School The University of Texas at Austin US Acute Care Solutions Canton Ohio USA

6. Division of Medical Toxicology Department of Emergency Medicine University of California Los Angeles Los Angeles California USA

7. Department of Emergency Medicine Cleveland Clinic Akron Ohio USA

8. Departments of Pediatrics and Emergency Medicine Emory University School of Medicine Children's Healthcare of Atlanta, Egleston Atlanta Georgia USA

9. Departments of Pediatrics and Emergency Medicine Seattle Children's Hospital Harborview Medical Center Seattle Washington USA

10. Department of Emergency Medicine Prisma Health Greenville South Carolina USA

Abstract

AbstractRecent increases in pediatric and adolescent opioid fatalities mandate an urgent need for early consideration of possible opioid exposure and specific diagnostic and management strategies and interventions tailored to these unique populations. In contrast to adults, pediatric methods of exposure include accidental ingestions, prescription misuse, and household exposure. Early recognition, appropriate diagnostic evaluation, along with specialized treatment for opioid toxicity in this demographic are discussed. A key focus is on Naloxone, an essential medication for opioid intoxication, addressing its unique challenges in pediatric use. Unique pediatric considerations include recognition of accidental ingestions in our youngest population, critical social aspects including home safety and intentional exposure, and harm reduction strategies, mainly through Naloxone distribution and education on safe medication practices. It calls for a multifaceted approach, including creating pediatric‐specific guidelines, to combat the opioid crisis among children and to work to lower morbidity and mortality from opioid overdoses.

Publisher

Wiley

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