The potential of Ethiopian medicinal plants to treat emergent viral diseases

Author:

Fekadu Mekbib12ORCID,Lulekal Ermias2,Tesfaye Solomon34,Ruelle Morgan5,Asfaw Nigist6,Awas Tesfaye7,Balemie Kebu7,Asres Kaleab3ORCID,Guenther Sebastian4,Asfaw Zemede2,Demissew Sebsebe2

Affiliation:

1. Plant Ecology and Geobotany, Faculty of Biology Philipps University of Marburg Marburg Germany

2. Department of Plant Biology and Biodiversity Management, College of Natural and Computational Sciences Addis Ababa University Addis Ababa Ethiopia

3. Department of Pharmaceutical Biology, Institute of Pharmacy Greifswald University Greifswald Germany

4. School of Pharmacy, College of Health Sciences Addis Ababa University Addis Ababa Ethiopia

5. Department of International Development, Community and Environment Clark University Worcester Massachusetts USA

6. Department of Chemistry, College of Natural and Computational Sciences Addis Ababa University Addis Ababa Ethiopia

7. Ethiopian Biodiversity Institute Addis Ababa Ethiopia

Abstract

AbstractEthiopians have deep‐rooted traditions of using plants to treat ailments affecting humans and domesticated animals. Approximately 80% of the population continues to rely on traditional medicine, including for the prevention and treatment of viral diseases. Many antiviral plants are available to and widely used by communities in areas where access to conventional healthcare systems is limited. In some cases, pharmacological studies also confirm the potent antiviral properties of Ethiopian plants. Building on traditional knowledge of medicinal plants and testing their antiviral properties may help to expand options to address the global pandemic of COVID‐19 including its recently isolated virulent variants and prepare for similar outbreaks in the future. Here, we provide an ethnobotanical and pharmacological inventory of Ethiopian medicinal plants that might contribute to the prevention and treatment of viral diseases. We identified 387 species, about 6% of Ethiopia's known flora, for which records of use by local communities and traditional herbalists have been documented for the treatment of viral diseases. We provide a framework for further investigation and development of this vital resource much anticipated to help combat emergent viral diseases along with existing ones in Ethiopia and elsewhere.

Publisher

Wiley

Subject

Pharmacology

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