Peripheral parenteral nutrition

Author:

Anderson A D G1,Palmer D1,MacFie J1

Affiliation:

1. Combined Gastroenterology Department, Scarborough Hospital, Woodlands Drive, Scarborough YO12 6QL, UK

Abstract

Abstract Background Peripheral parenteral nutrition (PPN) currently accounts for almost 20 per cent of all parenteral nutrition administered in the UK. In the absence of consensus guidelines there is wide variation in practice. Heterogeneity of clinical trials has made direct comparisons difficult and meta-analysis impossible. Methods Medline, Embase and Cochrane databases were searched for all clinical trials relating to the use of PPN in adults. Relevant papers from the reference lists of these articles and from the authors' personal collections were also reviewed. Results and conclusions Effective PPN is possible in about 50 per cent of inpatients requiring parenteral nutrition. Evidence relating to optimal feed composition, choice of cannula, infusion technique and pharmacological manipulation is discussed, along with practical recommendations for the administration of PPN.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference56 articles.

1. First choice for total parenteral nutrition: the peripheral route;Payne-James;JPEN J Parenter Enteral Nutr,1993

2. Intravenous nutrition: the central or peripheral route?;Hansell;Intensive Ther Clin Monit,1989

3. Intravenous infusion of fat emulsions, phosphatides and emulsifying agents;Schuberth;Acta Chir Scand Suppl,1961

4. Metabolic studies in total parenteral nutrition with lipid in man. Comparison with glucose;Jeejeehoy;J Clin Invest,1976

5. Glucose or fat as non-protein energy source? A controlled clinical trial in gastroenterological patients requiring intravenous nutrition;MacFie;Gastroenterology,1981

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