Effect of ciclosporin on clinical signs of degenerative mucinotic mural folliculitis in a young cat

Abstract

AbstractA 1.5‐year‐old, spayed, female, mixed‐breed cat that had been housed completely indoors presented with a chief complaint of facial hair loss. Alopecia extended from the face to the outside of the auricle, and was accompanied by thickening of the dorsal eyelid and scales on the dorsal chest. Histopathological examination revealed infiltration of lymphocytes targeting the hair follicle wall and deposition of mucin in the isthmus of hair follicles. A diagnosis of degenerative mucinotic mural folliculitis was obtained based on the clinical and histological findings. The cat was treated with ciclosporin (9.3 mg/kg) administered once daily. The alopecia and thickening resolved, and the general condition improved. The cat was clinically well for 10 months. The cat has survived 14 months since treatment was started. This case demonstrates the efficacy of high‐dose ciclosporin in treating degenerative mucinotic mural folliculitis.