Brownian dynamic study of an enzyme metabolon in the TCA cycle: Substrate kinetics and channeling

Author:

Huang Yu-ming M.1,Huber Gary A.2,Wang Nuo3,Minteer Shelley D.4,McCammon J. Andrew123

Affiliation:

1. Department of Pharmacology; University of California, San Diego; La Jolla California 92093

2. Howard Hughes Medical Institute, University of California, San Diego; La Jolla California 92093

3. Department of Chemistry and Biochemistry; University of California, San Diego; La Jolla California 92093

4. Department of Chemistry; The University of Utah; Salt Lake City Utah 84112

Funder

Howard Hughes Medical Institute

National Institutes of Health

NBCR NIH

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference23 articles.

1. Respiratory metabolism: glycolysis, the TCA cycle and mitochondrial electron transport;Fernie;Curr Opin Plant Biol,2004

2. Krebs citric-acid cycle: half a century and still turning-introductory;Kornberg;Biochem Soc Symp,1987

3. Organization of Krebs tricarboxylic-acid cycle enzymes in mitochondria;Robinson;J Biol Chem,1985

4. Multi-enzyme systems: bringing enzymes together in vitro;Schoffelen;Soft Matter,2012

5. Metabolic compartmentation: symbiotic, organellar, multienzymic, and microenvironmental;Srere;Annu Rev Microbiol,1974

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