Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies

Author:

Ejima Daisuke,Tsumoto Kouhei,Fukada Harumi,Yumioka Ryosuke,Nagase Kazuo,Arakawa Tsutomu,Philo John S.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference24 articles.

1. The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein;Vermeer;Biophys J,2000

2. Non-native conformational states of immunoglobulins: Thermodynamic and functional studies of rabbit IgG;Vlasov;Biochemistry (Moscow),1996

3. Thermodynamic and functional characterization of a stable IgG conformer obtained by renaturation fro a partially structured low pH-induced state;Martsev;FEBS Lett,1995

4. Temperature and pH dependence of immunoglobulin conformation;Calmettes;Arch Biochem Biophys,1991

5. Alternatively folded states of an immunoglobulin;Buchner;Biochemistry,1991

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