First trimester screening for Down syndrome using nuchal translucency, maternal serum pregnancy-associated plasma protein A, free-β human chorionic gonadotrophin, placental growth factor, and α-fetoprotein

Author:

Huang Tianhua1,Dennis Alan1,Meschino Wendy S.12,Rashid Shamim1,Mak-Tam Ellen1,Cuckle Howard3

Affiliation:

1. Genetics Program; North York General Hospital; Toronto Ontario Canada

2. Department of Paediatrics; University of Toronto; Toronto Ontario Canada

3. Department of Obstetrics and Gynecology; Columbia University Medical Center; New York NY USA

Funder

Nork York General Hospital

Publisher

Wiley

Subject

Genetics(clinical),Obstetrics and Gynaecology

Reference49 articles.

1. Prospective experience with integrated prenatal screening and first trimester combined screening for trisomy 21 in a large Canadian urban center;Okun;Prenat Diagn,2008

2. First-trimester screening for trisomies 21, 18 and 13 by ultrasound and biochemical testing;Wright;Fetal Diagn Ther,2014

3. Contingent screening for Down syndrome--results from the FaSTER trial;Cuckle;Prenat Diagn,2008

4. First and second trimester antenatal screening for Down's syndrome: the results of the serum, urine and ultrasound screening study (SURUSS);Wald;J Med Screen,2003

5. Combined screening for preeclampsia and small for gestational age at 11-13 weeks;Poon;Fetal Diagn Ther,2013

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