Morin enhances auranofin anticancer activity by up‐regulation of DR4 and DR5 and modulation of Bcl‐2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells

Author:

Hwang‐Bo Hyun12,Lee Won Sup3ORCID,Nagappan Arulkumar3,Kim Hong Jae4ORCID,Panchanathan Radha3,Park Cheol5,Chang Seong‐Hwan6,Kim Nam Deuk4,Leem Sun‐Hee7,Chang Young‐Chae8,Kwon Taeg Kyu9,Cheong Jae Hun2,Kim Gon Sup10ORCID,Jung Jin‐Myung11,Shin Sung Chul12,Hong Soon Chan13,Choi Yung Hyun1

Affiliation:

1. Department of BiochemistryDongeui University College of Korean Medicine and Anti‐Aging Research Center, Dongeui University Busan South Korea

2. Department of Molecular BiologyPusan National University Busan South Korea

3. Department of Internal Medicine, Institute of Health Sciences, and Gyeongsang National University HospitalGyeongsang National University School of Medicine Jinju South Korea

4. Department of Pharmacy, College of PharmacyPusan National University Busan South Korea

5. Department of Molecular BiologyDongeui University Busan Republic of Korea

6. Department of SurgeryKonkuk University School of Medicine Seoul South Korea

7. Department of Biological ScienceDong‐A University Busan South Korea

8. Research Institute of Biomedical Engineering and Department of MedicineCatholic University of Daegu School of Medicine Daegu South Korea

9. Department of Immunology, School of MedicineKeimyung University Daegu South Korea

10. School of Veterinary Medicine, Research Institute of Life ScienceGyeongsang National University Jinju South Korea

11. Department of Neurosurgery, Institute of Health SciencesGyeongsang National University School of Medicine Jinju Republic of Korea

12. Department of Chemistry, Research Institute of Life ScienceGyeongsang National University Jinju South Korea

13. Department of Surgery, Institute of Health SciencesGyeongsang National University School of Medicine Jinju South Korea

Funder

National Research Foundation of Korea

Publisher

Wiley

Subject

Pharmacology

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