Ordinal Outcomes Are Superior to Binary Outcomes for Designing and Evaluating Clinical Trials in Compensated Cirrhosis-Reference-Cited by-同舟云学术

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Ordinal Outcomes Are Superior to Binary Outcomes for Designing and Evaluating Clinical Trials in Compensated Cirrhosis

Published:2020-07-06 Issue:3 Volume:72 Page:1029-1042
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

D’Amico Gennaro¹^ORCID,Abraldes Juan G.²,Rebora Paola³,Valsecchi Maria Grazia³,Garcia‐Tsao Guadalupe⁴

Affiliation:

1. Gastroenterology Unit Ospedale V. Cervello, Clinica La Maddalena Palermo Italy

2. Division of Gastroenterology (Liver Unit), Department of Medicine CEGIIR, University of Alberta Edmonton AB Canada

3. Dipartimento di Medicina e Chirurgia Università di Milano‐Bicocca Milano Italy

4. Section of Digestive Diseases Yale University School of Medicine/VA‐CT Healthcare System New Haven CT

Funder

Yale Liver Center

Publisher

Wiley

Subject

Hepatology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep.31070

Reference22 articles.

1. Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies

2. Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

3. β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial

4. Beta-Blockers to Prevent Gastroesophageal Varices in Patients with Cirrhosis

5. Statistical assessment of ordinal outcomes in comparative studies

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1. A roadmap for clinical trials in MASH-related compensated cirrhosis;Nature Reviews Gastroenterology & Hepatology;2024-07-17

2. Opportunities for more powerful statistical analyses of ordinal scales: A scoping review of neurological trials;2024-06-24

3. A Bayesian quasi-likelihood design for identifying the minimum effective dose and maximum utility dose in dose-ranging studies;Statistical Methods in Medical Research;2024-04-04

4. Optimising the analysis of vascular prevention trials: Re-Assessment of the TARDIS trial, the first prevention trial to adopt an ordinal primary outcome measure;Contemporary Clinical Trials Communications;2023-10

5. Distinct on-treatment HCC risks associated with different decompensation events in HBV patients with cirrhosis;Hepatology International;2023-08-19

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