Comparison of 6-mercaptopurine with 6-thioguanine for the analysis of thiopurine S- methyltransferase activity in human erythrocyte by LC-MS/MS

Author:

Mei Shenghui12,Li Xindi34,Gong Xiaoqing34,Zhang Xiaoyi5,Li Xingang12,Yang Li12,Zhu Leting1,Zhou Heng34,Liu Yonghong34,Zhou Anna34,Zhang Xinghu34,Zhao Zhigang1ORCID

Affiliation:

1. Department of Pharmacy, Beijing Tiantan Hospital; Capital Medical University; Beijing People's Republic of China

2. Department of Clinical Pharmacology, College of Pharmaceutical Sciences; Capital Medical University; Beijing People's Republic of China

3. Neuroinfection and Neuroimmunology Center; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University; Beijing People's Republic of China

4. China National Clinical Research Center for Neurological Diseases; Beijing Tiantan Hospital, Capital Medical University; Beijing People's Republic of China

5. College of Pharmaceutical Sciences; Capital Medical University; Beijing People's Republic of China

Funder

Beijing Municipal Science & Technology Commission

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference33 articles.

1. Thiopurine methyltransferase activity: New conditions for reversed-phase high-performance liquid chromatographic assay without extraction and genotypic-phenotypic correlation;Anglicheau;Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences,2002

2. Mechanism of allopurinol induced TPMT inhibition;Blaker;Biochemical Pharmacology,2013

3. Bland , J. M. 2004 How can I decide the sample size for a study of agreement between two methods of measurement? http://www-users.york.ac.uk/~mb55/meas/sizemeth.htm

4. Statistical methods for assessing agreement between two methods of clinical measurement;Bland;Lancet,1986

5. Comparing methods of measurement: Why plotting difference against standard method is misleading;Bland;Lancet,1995

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