Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease

Author:

Liberal Rodrigo1,Grant Charlotte R.1,Longhi Maria Serena1,Mieli-Vergani Giorgina1,Vergani Diego1

Affiliation:

1. Institute of Liver Studies and Paediatric Liver, GI & Nutrition Centre; King's College London School of Medicine at King's College Hospital; London UK

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Genetics,Molecular Biology,Biochemistry

Reference123 articles.

1. Cell interactions in the induction of tolerance: the role of thymic lymphocytes;Gershon;Immunology,1970

2. The stimulation of specific suppressor T cells in genetic non-responder mice by linear random copolymers of l-amino acids;Benacerraf;Transplant. Rev.,1975

3. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

4. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state;Takahashi;Int. Immunol.,1998

5. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production;Thornton;J. Exp. Med.,1998

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