Preclinical evaluation of the pharmacokinetics, brain uptake and metabolism of E121, an antiepileptic enaminone ester, in rats-Reference-Cited by-同舟云学术

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Preclinical evaluation of the pharmacokinetics, brain uptake and metabolism of E121, an antiepileptic enaminone ester, in rats

Published:2003 Issue:9 Volume:24 Page:397-407
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Khurana Manoj,Salama Noha N.,Scott Kenneth R.,Nemieboka Noble N.,Bauer Kenneth S.,Eddington Natalie D.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference32 articles.

1. The clinical impact of new antiepileptic drugs after a decade of use in epilepsy

2. New horizons in the development of antiepileptic drugs

3. Profile of Anticonvulsant Activity and Minimal Toxicity of Methyl 4-[(p-Chlorophenyl)amino]-6-Methyl-2-Oxo-Cyclohex-3-En-l-Oate and Some Prototype Antiepileptic Drugs in Mice and Rats

4. Synthesis and Anticonvulsant Activity of Enaminones. 3. Investigations on 4'-, 3'-, and 2'-Substituted and Polysubstituted Anilino Compounds, Sodium Channel Binding Studies, and Toxicity Evaluations1,2

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bioactivity of benzophenazine enaminone derivatives as inhibitors of ERK2 based on molecular docking and dynamics simulation studies;New Journal of Chemistry;2024

2. Green synthesis of new lawsone enaminones and their Z/E(CC)-isomerization induced by organic solvent;RSC Advances;2021

3. One-Pot Synthesis, X-ray Single Crystal and Molecular Insight of Enaminone-Based β-Morpholino-/N-Methylpiperazinyl-/Pyrrolidinylpropiophenone;Crystals;2020-04-08

4. Crystal Structure and Quantum Chemical Studies of a Novel Push–Pull Enaminone: 3-Chloro-4-((4-bromophenyl)amino)pent-3-en-2-one;Journal of Chemical Crystallography;2019-05-20

5. Synthesis of novel pyrazole incorporating a coumarin moiety (PC) for selective and sensitive Co2+ detection;New Journal of Chemistry;2019

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