Affiliation:
1. Departamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica “Enrique Moles” and Centro de Innovación en Química Avanzada (ORFEO-CINQA) Universidad de Oviedo Julián Clavería, 8 33006 Oviedo Spain
Abstract
AbstractThe photochemical catalyst‐free radical‐based synthesis of vinyl and 1,3‐dienyl sulfones is disclosed. Mechanistic investigations support that the transformations rely on a visible‐light‐promoted activation of a halogen‐bonding complex, which is formed between an alkenyl (or 1,3‐dienyl) bromide and a sodium sulfinate salt. The reactions exhibit a wide functional group tolerance (compatible with heteroatoms, electron‐withdrawing and electron‐donating groups), finding application in the structural modification of biologically relevant molecules. Eventually, a continuous flow protocol was developed to upscale these transformations.
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献