Visible‐Light‐Driven Copper‐Catalyzed Synthesis of Sulfonamides from Aryl‐N2BF4 through One‐pot Tricomponent Reaction

Abstract

AbstractA method for preparing sulfonamides using visible light is described. In this approach, an aryl diazo tetrafluoroborate salt, 1,4‐diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO), and amino benzoate as substrates, CuBr2 as a catalyst, and 3‐methyl‐3‐pentanol as an additive were employed for a one‐pot multicomponent reaction to provide sulfonamides under mild reaction conditions. A variety of aryl diazo tetrafluoroborate salts and O‐benzoyl hydroxylamines were tolerated in this process to provide products with yields up to 96%.magnified image