Affiliation:
1. Key Laboratory of Organic Chemistry of Jiangxi Province Jiangxi Science & Technology Normal University Nanchang 330013 People's Republic of China
Abstract
AbstractAn electrocatalytic approach for the bromide‐mediated selenocyclization of N‐propargylamides with diselenides is described, providing a synthetic route for the synthesis of various seleno‐oxazoles in 41–73% yields. The success of gram‐scale experiments demonstrate the potential value of this protocol in synthetic chemistry. Mechanistic investigations suggest that this selenocyclization protocol proceed through two possible pathways, including selenium cation and radical processes.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Jiangxi Province
Education Department of Jiangxi Province