Electrochemical Selenylation‐Induced Annulation of Alkenyl Ureas to Access Cyclic Isoureas

Author:

Li Hongjun1ORCID,Tang Dong2ORCID,Zhou Pengjuan2,Wan Yaya2,Jiang Rui2,Yang Jinhui1ORCID

Affiliation:

1. State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering College of Chemistry and Chemical Engineering Ningxia University 750021 Yinchuan People's Republic of China

2. Ningxia Center of Agricultural Organic Synthesis Agricultural Resource and Environment Institute of Ningxia Academy of Agriculture and Forestry Science 750002 Yinchuan People's Republic of China

Abstract

AbstractA direct electrosynthesis of cyclic isoureas from N‐allyl ureas and diselenides has been described. This protocol proceeds without any additional catalyst and oxidant, at room temperature under air, providing the desired products in 71–91% yield. In addition, the synthesis of cyclic isoureas containing five to seven‐membered rings has also been achieved by the employment of this strategy. On the basis of the mechanism experiments and previous research works, a probable mechanism is proposed.

Funder

Natural Science Foundation of Ningxia Province

National Natural Science Foundation of China

Chinese Academy of Engineering

Publisher

Wiley

Subject

General Chemistry

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