Robust Bayesian nonlinear mixed-effects modeling of time to positivity in tuberculosis trials
Author:
Affiliation:
1. Department of Statistics; University of Pretoria; Pretoria South Africa
2. Department of Mathematical Statistics and Actuarial Science; University of the Free State; Bloemfontein South Africa
3. IQVIA, Biostatistics; Bloemfontein South Africa
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/pst.1877/fullpdf
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2. Modelling of mycobacterial load reveals bedaquiline's exposure-response relationship in patients with drug-resistant TB;Svensson;J Antimicrob Chemother,2017
3. Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials;Phillips;BMC Med,2016
4. Biomarkers for tuberculosis disease activity, cure, and relapse;Wallis;Lancet Infect Dis,2009
5. Evaluation of time to detection of Mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials;Weiner;J Clin Microbiol,2010
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