Lifetime occupational skill and later‐life cognitive function among older adults in the United States, Mexico, India, and South Africa

Author:

Kobayashi Lindsay C.123ORCID,O'Shea Brendan Q.1,Wixom Caroline2,Jones Richard N.45,Langa Kenneth M.2678,Weir David2,Lee Jinkook910,Wong Rebeca11,Gross Alden L.12

Affiliation:

1. Center for Social Epidemiology and Population Health Department of Epidemiology University of Michigan School of Public Health Ann Arbor USA

2. Survey Research Center Institute for Social Research University of Michigan Ann Arbor USA

3. MRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt) University of the Witwatersrand Johannesburg South Africa

4. Department of Psychiatry and Human Behavior Alpert Medical School Brown University Providence USA

5. Department of Neurology Alpert Medical School Brown University Providence USA

6. Department of Internal Medicine School of Medicine University of Michigan Ann Arbor USA

7. Institute for Healthcare Policy and Innovation University of Michigan Ann Arbor USA

8. Veterans Affairs Ann Arbor Center for Clinical Management Research Ann Arbor Michigan USA

9. Center for Economic and Social Research University of Southern California Los Angeles California USA

10. Department of Economics University of Southern California Los Angeles California USA

11. Sealy Center on Aging University of Texas Medical Branch Galveston Texas USA

12. Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore USA

Abstract

AbstractINTRODUCTIONWe conducted a cross‐national comparison of the association between main lifetime occupational skills and later‐life cognitive function across four economically and socially distinct countries.METHODSData were from population‐based studies of aging and their Harmonized Cognitive Assessment Protocols (HCAPs) in the US, South Africa, India, and Mexico (N = 10,037; Age range: 50 to 105 years; 2016 to 2020). Main lifetime occupational skill was classified according to the International Standard Classification of Occupations. Weighted, adjusted regression models estimated pooled and country‐specific associations between main lifetime occupational skill and later‐life general cognitive function in men and women.RESULTSWe observed positive gradients between occupational skill and later‐life cognitive function for men and women in the US and Mexico, a positive gradient for women but not men in India, and no association for men or women in South Africa.DISCUSSIONMain lifetime occupations may be a source of later‐life cognitive reserve, with cross‐national heterogeneity in this association.Highlights No studies have examined cross‐national differences in the association of occupational skill with cognition. We used data from Harmonized Cognitive Assessment Protocols in the US, Mexico, India, and South Africa. The association of occupational skill with cognitive function varies by country and gender.

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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