Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors

Author:

Woerner Stefan M.12,Tosti Elena3,Yuan Yan P.42,Kloor Matthias125,Bork Peer42,Edelmann Winfried3,Gebert Johannes125

Affiliation:

1. Department of Applied Tumor Biology; Institute of Pathology; University Hospital Heidelberg; Heidelberg Germany

2. Molecular Medicine Partnership Unit; University of Heidelberg and European Molecular Biology Laboratory; Heidelberg Germany

3. Department of Cell Biology; Albert Einstein College of Medicine; New York NY

4. Structural and Computational Biology Unit; European Molecular Biology Laboratory; Heidelberg Germany

5. Clinical Cooperation Unit Applied Tumor Biology; DKFZ Heidelberg Germany

Funder

University Hospital Heidelberg

The European Molecular Biology Laboratory

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference45 articles.

1. Mechanisms in eukaryotic mismatch repair;Modrich;J Biol Chem,2006

2. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression;Deng;Cancer Res,1999

3. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer;Fishel;Cell,1993

4. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer;Leach;Cell,1993

5. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer;Bronner;Nature,1994

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