Differences in heart failure with preserved ejection fraction management between care providers: an international survey

Author:

Guidetti Federica1,Giraldo Clara Inés Saldarriaga2,Shchendrygina Anastasia3,Kida Keisuke4,Niederseer David567,Basic Carmen89,Rainer Peter P.101112,Załęska‐Kocięcka Marta13,Ogola Elijah14,Mohty Dania1516,Lanfranchi Giuseppina17,Sari Novi Yanti18,Einarsson Hafsteinn19,Zurek Marzena20,Ruschitzka Frank720,Savarese Gianluigi121,Mewton Nathan22

Affiliation:

1. Division of Cardiology, Department of Medicine Karolinska Institutet Stockholm Sweden

2. Pontificia Bolivariana, University of Antioquia, Cardiovid Clinic Medellin Colombia

3. IM Sechenov First Moscow State Medical University Moscow Russia

4. Department of Pharmacology St Marianna University School of Medicine Kawasaki Japan

5. Hochgebirgsklinik Davos, Medicine Campus Davos Davos Switzerland

6. Christine Kuhne Center for Allergy Research and Education (CK‐CARE), Medicine Campus Davos Davos Switzerland

7. Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology University Hospital Zurich, University of Zurich Zurich Switzerland

8. Department of Medicine Geriatrics and Emergency Medicine/stra Region Vstra Gtaland, Sahlgrenska University Hospital Gothenburg Sweden

9. Department of Molecular and Clinical Medicine, Institute of Medicine University of Gothenburg, Sahlgrenska Academy Gothenburg Sweden

10. Department of Cardiology Medical University of Graz Graz Austria

11. BioTechMed Graz Graz Austria

12. St. Johann in Tirol General Hospital St. Johann in Tirol Austria

13. Department of Heart Failure and Transplantology, Department of Mechanical Circulatory Support and Transplantation National Institute of Cardiology Warsaw Poland

14. Department of Clinical Medicine and Therapeutics Faculty of Health Sciences, University of Nairobi Nairobi Kenya

15. Heart Center King Faisal Specialist Hospital and Research Center Riyadh Saudi Arabia

16. College of Medicine Al Faisal University Riyadh Saudi Arabia

17. Geriatric Departement, Hôpital Pierre Garraud Institut du Vieillissement, Hospices Civils de Lyon Lyon France

18. Department of Cardiology Dr. Muhammad Hoesin General Hospital Palembang Indonesia

19. Department of Computer Science University of Iceland Reykjavík Iceland

20. Department of Cardiology, University Heart Center University Hospital Zürich and University of Zürich Zürich Switzerland

21. Heart, Vascular and Neuro Theme, Karolinska University Hospital Stockholm Sweden

22. Hôpital Cardiovasculaire Louis Pradel Hospices Civils de Lyon, Heart Failure Department Clinical Investigation Center Inserm 1407 CarMeN Inserm 1060, University Claude Bernard Lyon Bron France

Abstract

AbstractAimsHeart failure (HF) with preserved ejection fraction (HFpEF) is characterized by growing incidence and poor outcomes. A large majority of HFpEF patients are cared by non‐cardiologists. The availability of sodium–glucose cotransporter 2 inhibitors (SGLT2i) as recommended therapy raises the importance of prompt and accurate identification and treatment of HFpEF across diverse healthcare settings. We evaluated HFpEF management across specialties through a survey targeting cardiologists, HF specialists, and non‐cardiologists.Methods and resultsAn independent web‐based survey was distributed globally between May and July 2023. We performed a post‐hoc analysis, comparing cardiologists, HF specialists, and non‐cardiologists. A total of 1460 physicians (61% male, median age 41[34–49]) from 95 countries completed the survey; 20% were HF specialists, 65% cardiologists, and 15% non‐cardiologists. Compared with HF specialists, non‐cardiologists and cardiologists were less likely to use natriuretic peptides (p = 0.003) and HFpEF scores (p = 0.004) for diagnosis, and were also less likely to have access to or consider specific echocardiographic parameters (p < 0.001) for identifying HFpEF. Diastolic stress tests were used in less than 30% of the cases, regardless of the specialty (p = 1.12). Multidrug treatment strategies were similar across different specialties. While SGLT2i and diuretics were the preferred drugs, angiotensin receptor blockers and angiotensin receptor–neprilysin inhibitors were the least frequently prescribed in all three groups. However, when constrained to choose one drug, the proportion of physicians favoring SGLT2i varied significantly among specialties (66% HF specialists, 52% cardiologists, 51% non‐cardiologists). Additionally, 10% of non‐cardiologists and 8% of cardiologists considered beta blocker the drug of choice for HFpEF.ConclusionSignificant differences among specialty groups were observed in HFpEF management, particularly in the diagnostic work‐up. Our results highlight a substantial risk of underdiagnosis and undertreatment of HFpEF patients, especially among non‐HF specialists.

Publisher

Wiley

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