Delivery of Stimulator of Interferon Genes (STING) Agonist Using Polypeptide‐Modified Dendrimer Nanoparticles in the Treatment of Melanoma
Author:
Affiliation:
1. Institute for Medical Engineering and Science Massachusetts Institute of Technology Cambridge MA 02139 USA
2. Department of Medicine Division of Engineering in Medicine Brigham and Women's Hospital Harvard Medical School Boston MA 02115 USA
Funder
Takeda Pharmaceuticals U.S.A.
Publisher
Wiley
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/anbr.202100006
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3. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
4. Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
5. The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
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