A Perspective on Ultrasound‐Triggered Production of Reactive Oxygen Species by Inorganic Nano/Microparticles

Author:

Han Yijun1,Yu Xinyue1,Marfavi Zeinab1,Chen Yumo1,Zhang Linxuan1,Chu Jing1,Sun Kang1,Li Mingda2,Tao Ke1ORCID

Affiliation:

1. State Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai 200240 P. R. China

2. School of Naval Architecture Ocean & Civil Engineering Shanghai Jiao Tong University Shanghai 200240 P. R. China

Abstract

Ultrasound can activate nano/microparticles to induce reactive oxygen species (ROS). The advantages of deep penetration and precise spatiotemporal control are demonstrated for multiple applications, such as sonodynamic therapy, chemical industry, and environmental treatment. Meanwhile, a toolbox of inorganic particles is developed to enhance ROS production via cavitation enhancement, sonoluminescence, and piezocatalytic effect. Nonetheless, sophisticated influences of ultrasonic parameters hamper further exploration of novel sonosensitized materials. In this perspective, the influential parameters in different mechanisms are reviewed, emphasizing the relationship between ultrasound frequency and catalytic activity, and outlooks are provided on the study of inorganic sonosensitizers.

Publisher

Wiley

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