Affiliation:
1. State Key Laboratory of Systems Medicine for Cancer School of Biomedical Engineering Institute of Medical Robotics and Med-X Research Institute Shanghai Jiao Tong University Shanghai 200030 P. R. China
2. Shanghai Key Laboratory of Gynecologic Oncology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200127 P. R. China
Abstract
Noble metal‐based nanomaterials have attracted tremendous attention in biomedical applications due to their unique electrical, optical, and chemical properties, playing crucial roles in the ultrasensitive detection of biomarkers, bioimaging, cancer therapy, etc. Especially, porous noble metal‐based nanomaterials show superior performance due to the large specific area and multiple active sites. Platforms constructed from porous noble metal‐based nanomaterials are emerging as highly promising tools for various biomedical applications. Herein, the properties and synthesis strategies of porous noble metal‐based nanomaterials are briefly introduced. Then the recent progress of porous noble metal‐based nanomaterials in the biomedical field is highlighted, focusing primarily on their applications in optics, electrochemistry, and mass spectrometry. Finally, the challenges related to fabrication and biocompatibility for their applications while also providing an outlook on their widespread use in clinical situations are discussed. This review aims to provide further insights into the design of porous noble metal‐based nanomaterials and expand their applications in the biomedical field.
Funder
National Key Research and Development Program of China
National Natural Science Foundation of China
China Postdoctoral Science Foundation
Shanghai Rising-Star Program
Institute of Molecular Medicine, School of Medicine, Shanghai Jiao Tong University