Isotope labeling to determine the dynamics of metabolic response in CHO cell perfusion bioreactors using MALDI-TOF-MS

Author:

Karst Daniel J.1,Steinhoff Robert F.2,Kopp Marie R. G.1,Soos Miroslav3,Zenobi Renato2,Morbidelli Massimo1ORCID

Affiliation:

1. Institute for Chemical and Bioengineering; Department of Chemistry and Applied Biosciences, ETH Zurich; Zurich 8093 Switzerland

2. Laboratory of Organic Chemistry; Department of Chemistry and Applied Biosciences, ETH Zurich; Zurich 8093 Switzerland

3. Department of Chemical Engineering; University of Chemistry and Technology, Technicka 3; Prague 166 28 Czech Republic

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Biotechnology

Reference36 articles.

1. Modulation of mAb quality attributes using microliter scale fed-batch cultures;Rouiller;Biotechnol Prog.,2014

2. Recombinant protein therapeutics from CHO cells-20 years and counting;Jayapal;Chem Eng Prog.,2007

3. The business impact of an integrated continuous biomanufacturing platform for recombinant protein production;Walther;J Biotechnol.,2015

4. Production processes of licensed recombinant factor VIII preparations;Boedeker;Semin Thromb Hemost.,2001

5. White paper on continuous bioprocessing. May 20-21, 2014 Continuous Manufacturing Symposium;Konstantinov;J Pharm Sci,2015

Cited by 28 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Perfusion process for CHO cell producing monoclonal antibody: Comparison of methods to determine optimum cell specific perfusion rate;Biochemical Engineering Journal;2023-02

2. Control of Continuous Manufacturing Processes for Production of Monoclonal Antibodies;Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing;2021-12-24

3. Index;Perfusion Cell Culture Processes for Biopharmaceuticals;2020-08-06

4. Mechanistic and Statistical Modelling of Bioprocesses;Perfusion Cell Culture Processes for Biopharmaceuticals;2020-08-06

5. Clinical- and Commercial-Scale Reactors;Perfusion Cell Culture Processes for Biopharmaceuticals;2020-08-06

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3