Characterization of the biochemical effects of naphthalene on the mouse respiratory system using NMR-based metabolomics

Author:

Hong Jia-Huei1,Lee Wen-Ching2,Hsu Yu-Ming3,Liang Hao-Jan1,Wan Cho-Hua4,Chien Chung-Liang2,Lin Ching-Yu1

Affiliation:

1. Institute of Environmental Health, College of Public Health; National Taiwan University; Taipei 10055 Taiwan Republic of China

2. Graduate Institute of Anatomy and Cell Biology, College of Medicine; National Taiwan University; Taipei 100 Taiwan Republic of China

3. Laboratory Animal Center, College of Medicine; National Taiwan University; Taipei 100 Taiwan Republic of China

4. Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine; National Taiwan University; Taipei 106 Taiwan Republic of China

Funder

National Health Research Institutes

National Science Council

Publisher

Wiley

Subject

Toxicology

Reference50 articles.

1. Breath alkanes as a marker of oxidative stress in different clinical conditions;Aghdassi;Free Radic. Biol. Med.,2000

2. Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition;Azmi;Biomarkers,2005

3. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts;Beckonert;Nat Protocols,2007

4. A rapid method of total lipid extraction and purification;Bligh;Can. J. Biochem. Physiol.,1959

5. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey;Buckpitt;J. Pharmacol. Exp. Ther.,1992

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