Probing ligand binding modes of human cytochrome P450 2J2 by homology modeling, molecular dynamics simulation, and flexible molecular docking

Author:

Li Weihua,Tang Yun,Liu Hong,Cheng Jiagao,Zhu Weiliang,Jiang Hualiang

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference59 articles.

1. Summary of information on human CYP enzymes: human P450 metabolism data;Rendic;Drug Metab Rev,2002

2. Cloning of CYP2J2 gene and identification of functional polymorphisms;King;Mol Pharmacol,2002

3. CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance;Zeldin;Mol Pharmacol,1996

4. Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart;Wu;J Biol Chem,1996

5. Distribution of soluble epoxide hydrolase and of cytochrome P4502C8, 2C9, and 2J2 in human tissues;Enayetallah;J Histochem Cytochem,2004

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