Validation of a HPLC-ESI MS/MS method for the determination of clonidine in human plasma and its application in a bioequivalence study in Chinese healthy volunteers

Author:

Zhuang Jialang1ORCID,Chen Jiangying1,Wang Xueding1,Pang Yin2,Bi Huichang1,Huang Lihui1,Zeng Guixiong1,Liao Xiaoxing3,Ma Zhongfu3,Chen Xiao3,Zhong Guoping1,Huang Min1,Zhao Xianglan1

Affiliation:

1. Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences; Sun Yat-Sen University; Guang Zhou 510006 China

2. Sun Yat-sen University Cancer Center; Guang Zhou 510060 China

3. The First Affiliated Hospital; Sun Yat-Sen University; Guang Zhou 510080 China

Funder

Major Production of New Medicine

Guangdong Major Production of New Medicine

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

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