Physical activity offsets genetic risk for incident depression assessed via electronic health records in a biobank cohort study

Author:

Choi Karmel W.1234ORCID,Zheutlin Amanda B.34,Karlson Rebecca A.3,Wang Min‐Jung23ORCID,Dunn Erin C.134ORCID,Stein Murray B.567ORCID,Karlson Elizabeth W.8,Smoller Jordan W.1234ORCID

Affiliation:

1. Department of PsychiatryMassachusetts General Hospital Boston Massachusetts

2. Department of EpidemiologyHarvard T.H. Chan School of Public Health Boston Massachusetts

3. Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic MedicineMassachusetts General Hospital Boston Massachusetts

4. Stanley Center for Psychiatric ResearchBroad Institute Boston Massachusetts

5. Department of Family Medicine and Public HealthUniversity of California San Diego La Jolla California

6. Department of PsychiatryUniversity of California San Diego La Jolla California

7. VA San Diego Healthcare System San Diego California

8. Department of Medicine, Division of Rheumatology, Inflammation and ImmunityBrigham and Women's Hospital Boston Massachusetts

Funder

National Human Genome Research Institute

National Institute of Mental Health

Publisher

Wiley

Subject

Psychiatry and Mental health,Clinical Psychology

Reference28 articles.

1. Compendium of Physical Activities: classification of energy costs of human physical activities

2. Physical activity, exercise, and physical fitness: Definitions and distinctions for health‐related research;Caspersen C. J.;Public Health Reports (Washington, D.C.: 1974),1985

3. Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study

4. Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults

5. Prospective study of polygenic risk, protective factors, and incident depression following combat deployment in US army soldiers;Choi K. W.;Psychological Medicine,2018

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