Bioequivalence of Ertugliflozin/Metformin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components

Author:

Dawra Vikas Kumar1,Liang Yali1,Wei Hua2,Pelletier Kathleen1,Shi Haihong1,Hickman Anne1,Bass Almasa3,Terra Steven G.4,Zhou Susan5,Krishna Rajesh5,Sahasrabudhe Vaishali1

Affiliation:

1. Pfizer Inc. Groton CT USA

2. Pfizer Shanghai China

3. Pfizer Inc. Durham NC USA

4. Pfizer Inc. Andover MA USA

5. Merck & Co., Inc. Kenilworth NJ USA

Funder

Merck Sharp and Dohme

Pfizer

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference26 articles.

1. Centers for Disease Control and Prevention.National diabetes statistics report 2017.https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf. Published 2017. Accessed January 22 2019.

2. International Diabetes Federation. IDF Diabetes Atlas 8th edn.Brussels Belgium: International Diabetes Federation.http://diabetesatlas.org/resources/2017-atlas.html. Published 2017. Accessed January 22 2019.

3. Renal sodium-glucose cotransporter inhibition in the management of type 2 diabetes mellitus

4. Pharmacokinetics, Pharmacodynamics and Clinical Use of SGLT2 Inhibitors in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease

5. Effect of food on the pharmacokinetics of ertugliflozin and its fixed‐dose combinations ertugliflozin/sitagliptin and ertugliflozin/metformin;Sahasrabudhe V;Clin Pharmacol Drug Dev

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