Entecavir‐induced neutropenia in an adult living donor liver transplant recipient: Successful conversion to tenofovir alafenamide

Author:

Lim I. Vern1ORCID,Yurttaş Nurgül Özgür2,Ayer Mesut2,Poturoğlu Şule3,Kınacı Erdem1,Özden İlgin1ORCID

Affiliation:

1. Department of General Surgery, Liver Transplantation & Hepatopancreatobiliary Surgery Unit Başakşehir Çam & Sakura City Hospital Istanbul Turkey

2. Department of Internal Medicine, Division of Hematology Başakşehir Çam & Sakura City Hospital Istanbul Turkey

3. Department of Internal Medicine, Division of Gastroenterology Başakşehir Çam & Sakura City Hospital Istanbul Turkey

Abstract

Key Clinical MessageAt 22 weeks post‐transplantation for HBV‐related cirrhosis, an adult woman developed neutropenia which was aggravated by COVID‐19 (ANC 0.4 × 109/L). Covid resolution and all “conventional” modifications were ineffective. Success within 2 weeks was achieved by switching entecavir to tenofovir alafenamide. A step‐by‐step judicious approach to post‐transplant neutropenia is vital.

Publisher

Wiley

Subject

General Medicine

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1. Multiple drugs;Reactions Weekly;2023-12-02

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