Total flavonoids from the dried root of <i>Tetrastigma hemsleyanum</i> Diels et Gilg inhibit colorectal cancer growth through <scp>PI3K</scp> / <scp>AKT</scp> / <scp>mTOR</scp> signaling pathway-Reference-Cited by-同舟云学术

Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K / AKT / mTOR signaling pathway

Published:2022-07-13 Issue:11 Volume:36 Page:4263-4277
ISSN:0951-418X
Container-title:Phytotherapy Research
language:en
Short-container-title:Phytotherapy Research

Author:

Zhai Yufei¹,Sun Jing¹,Sun Chengtao¹,Zhao Huan¹,Li Xuan¹,Yao Jiaxiong¹,Su Jiajia¹,Xu Xiaoqian¹,Xu Xiukun²,Hu Jiangning³,Daglia Maria⁴⁵,Han Bing¹,Kai Guoyin¹^ORCID

Affiliation:

1. Laboratory for Core Technology of TCM Quality Improvement and Transformation, College of Pharmaceutical Sciences, The Second Affiliated Hospital, Academy of Chinese Medical Science Zhejiang Chinese Medical University Hangzhou China

2. Wenling Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University Taizhou China

3. Zhejiang Conba Pharmaceutical Limited Company Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine Pharmaceutical Technology Hangzhou China

4. Department of Pharmacy University of Napoli Federico II Naples Italy

5. International Research Center for Food Nutrition and Safety Jiangsu University Zhenjiang China

Funder

National Natural Science Foundation of China

Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7561

Reference37 articles.

1. Isoquercitrin inhibits bladder cancer progression in vivo and in vitro by regulating the PI3K/Akt and PKC signaling pathways

2. Biological effects and mechanisms of matrine and other constituents of Sophora flavescens in colorectal cancer

3. Colorectal Cancer and Dysplasia in Inflammatory Bowel Disease: A Review of Disease Epidemiology, Pathophysiology, and Management

4. Molecular docking of potential inhibitors with the mTOR protein

5. Antitumor activity of total flavonoids from Tetrastigma hemsleyanum Diels et Gilg is associated with the inhibition of regulatory T cells in mice;Feng Z.;Oncotargets and Therapy,2014

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