Affiliation:
1. CAS Key Laboratory of Design and Assembly of Functional Nanostructures State Key Laboratory of Structural Chemistry and Fujian Key Laboratory of Nanomaterials Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fuzhou Fujian 350002 China
2. University of Chinese Academy of Sciences Beijing 100049 China
3. Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou Fujian 350108 China
Abstract
AbstractThe growing crisis of antibiotic resistance calls for advanced and sustainable antibacterial strategies. In the past few years, lanthanide‐doped upconversion nanoparticles (UCNPs) with unique photophysical properties have been innovatively explored for bacterial detection and therapy, and hold promise for alleviating challenges faced in the post‐antibiotic era. In this review, the interface engineering for the bacteria‐targeted UCNP nanoplatforms is highlighted, the principles and merits of various upconversion detection strategies are discussed, and the latest progress in UCNP‐based antibacterial applications are summarized, especially in deep‐tissue infection imaging and therapy. Finally, the remaining concerns and future efforts for practical applications are put forward. This review is expected to provide comprehensive guidance for diagnosing and combating bacterial infections based on advanced UCNP nanoplatforms.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Fujian Province
Subject
Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials
Cited by
23 articles.
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