Affiliation:
1. Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA
2. Weill Cornell Medicine New York New York USA
3. Department of Pathology Memorial Sloan Kettering Cancer Center New York New York USA
4. Library Memorial Sloan Kettering Cancer Center New York New York USA
5. Department of Radiology Sloan Kettering Institute New York New York USA
Abstract
AbstractBackgroundPleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.MethodsWe reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.ResultsThe cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, p < 0.001), more often discovered incidentally on imaging (33%, n = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, p = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (n = 6, 4.1% vs. n = 1, 0.4%, p = 0.016).ConclusionsParotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.