Affiliation:
1. State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science Institute of Fiber Materials and Devices and Laboratory of Advanced Materials Fudan University Shanghai 200438 China
2. School of Information Science and Technology Fudan University Shanghai 200438 China
3. Department of Aeronautics and Astronautics Fudan University Shanghai 200433 China
Abstract
AbstractResearchers have typically studied the brain by monitoring characteristic signals, such as electrophysiology and neurotransmitters by implanted electronics. Here, real‐time monitoring of dynamic deformations of the brain tissue in vivo, is demonstrated, as a new characteristic parameter that is reflective of brain states. As a proof of concept, a thin capacitive deformation sensor is fabricated and implanted between the skull and cortex, and the sensor is shown to effectively monitor dynamic deformations of the cortical surface in the rat brain as induced by respiration and heartbeat under different degrees of anesthesia. This brain monitoring approach based on deformation signals opens up a new direction for understanding the brain.
Funder
Ministry of Science and Technology of the People's Republic of China
National Natural Science Foundation of China
Science and Technology Commission of Shanghai Municipality