Global burden of 34 cancers among women in 2020 and projections to 2040: Population‐based data from 185 countries/territories

Author:

Bizuayehu Habtamu Mellie1ORCID,Dadi Abel F.23,Hassen Tahir A.4,Ketema Daniel Bekele56,Ahmed Kedir Y.7,Kassa Zemenu Y.89,Amsalu Erkihun1011,Kibret Getiye Dejenu612,Alemu Addisu Alehegn613,Alebel Animut614,Shifa Jemal E.9,Assefa Yibeltal1,Tessema Gizachew A.1516,Sarich Peter17,Gebremedhin Aster Ferede614,Bore Meless G.8ORCID

Affiliation:

1. School of Public Health, Faculty of Medicine The University of Queensland Brisbane Queensland Australia

2. Menzies School of Health Research Charles Darwin University Casuarina Northern Territory Australia

3. Addis Continental Institute of Public Health Addis Ababa Ethiopia

4. Center for Women's Health Research, College of Health, Medicine and Wellbeing The University of Newcastle Newcastle New South Wales Australia

5. The George Institute for Global Health University of New South Wales (UNSW) Sydney New South Wales Australia

6. College of Medicine and Health science Debre Markos University Debre Markos Ethiopia

7. Rural Health Research Institute Charles Sturt University Orange New South Wales Australia

8. College of Medicine and Health Sciences Hawassa University Hawassa Ethiopia

9. School of Nursing and Midwifery University of Technology Sydney Sydney New South Wales Australia

10. Sydney Medical School, Faculty of Medicine and Health University of Sydney Sydney New South Wales Australia

11. St. Paul Hospital Millennium Medical College Addis Ababa Ethiopia

12. Faculty of Medicine, Health and Human Sciences Macquarie University Sydney New South Wales Australia

13. School of Women's and Children's Health University of New South Wales Sydney Sydney New South Wales Australia

14. School of Public Health, Faculty of Health University of Technology Sydney Ultimo New South Wales Australia

15. Curtin School of Population Health Curtin University Perth Western Australia Australia

16. School of Public Health University of Adelaide Adelaide South Australia Australia

17. The Daffodil Centre The University of Sydney, A Joint Venture with Cancer Council NSW Sydney New South Wales Australia

Abstract

AbstractGlobally women face inequality in cancer outcomes; for example, smaller improvements in life expectancy due to decreased cancer‐related deaths than men (0.5 vs 0.8 years, 1981–2010). However, comprehensive global evidence on the burden of cancer among women (including by reproductive age spectrum) as well as disparities by region, remains limited. This study aimed to address these evidence gaps by considering 34 cancer types in 2020 and their projections for 2040. The cancer burden among women in 2020 was estimated using population‐based data from 185 countries/territories sourced from GLOBOCAN. Mortality to Incidence Ratios (MIR), a proxy for survival, were estimated by dividing the age‐standardised mortality rates by the age‐standardised incidence rates. Demographic projections were performed to 2040. In 2020, there were an estimated 9.3 million cancer cases and 4.4 million cancer deaths globally. Projections showed an increase to 13.3 million (↑44%) and 7.1 million (↑60%) in 2040, respectively, with larger proportional increases in low‐ and middle‐income countries. MIR among women was higher (poorer survival) in rare cancers and with increasing age. Countries with low Human Development Indexes (HDIs) had higher MIRs (69%) than countries with very high HDIs (30%). There was inequality in cancer incidence and mortality worldwide among women in 2020, which will further widen by 2040. Implementing cancer prevention efforts and providing basic cancer treatments by expanding universal health coverage through a human rights approach, expanding early screening opportunities and strengthening medical infrastructure are key to improving and ensuring equity in cancer control and outcomes.

Publisher

Wiley

Subject

Cancer Research,Oncology

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