Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma

Author:

Lee Terence Kin-Wah12,Cheung Vincent Chi-Ho12,Lu Ping12,Lau Eunice Yuen Ting12,Ma Stephanie13,Tang Kwan Ho2,Tong Man3,Lo Jessica12,Ng Irene Oi Lin12

Affiliation:

1. State Key Laboratory for Liver Research; The University of Hong Kong; Pokfulam Hong Kong

2. Departments of Pathology; The University of Hong Kong; Pokfulam Hong Kong

3. Anatomy, Li Ka Shing Faculty of Medicine; The University of Hong Kong; Pokfulam Hong Kong

Funder

Research Grants Council of Hong Kong

Publisher

Wiley

Subject

Hepatology

Reference29 articles.

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2. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice;Lapidot;Nature,1994

3. Identification of a cancer stem cell in human brain tumors;Singh;Cancer Res,2003

4. A human colon cancer cell capable of initiating tumor growth in immunodeficient mice;O'Brien;Nature,2007

5. Identification and characterization of tumorigenic liver cancer stem/progenitor cells;Ma;Gastroenterology,2007

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