Lysosomal disruption by orthopedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms-Reference-Cited by-同舟云学术

Lysosomal disruption by orthopedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms

Published:2020-08-22 Issue:3 Volume:39 Page:493-505
ISSN:0736-0266
Container-title:Journal of Orthopaedic Research
language:en
Short-container-title:J Orthop Res

Author:

Fort Brian P.¹^ORCID,Dubyak George R.²,Greenfield Edward M.³⁴⁵⁶

Affiliation:

1. Department of Pathology, University Hospitals Cleveland Medical Center Case Western Reserve University School of Medicine Cleveland Ohio

2. Department of Physiology and Biophysics, University Hospitals Cleveland Medical Center Case Western Reserve University School of Medicine Cleveland Ohio

3. Department of Orthopaedics, Case Western Reserve University School of Medicine University Hospitals Cleveland Medical Center Cleveland Ohio

4. Department of Orthopaedic Surgery Indiana University School of Medicine Indianapolis Indiana

5. Department of Anatomy, Cell Biology, and Physiology Indiana University School of Medicine Indianapolis Indiana

6. Indiana Center for Musculoskeletal Health Indiana University School of Medicine Indianapolis Indiana

Funder

National Institutes of Health

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jor.24826

Reference50 articles.

1. Polyethylene wear rate and osteolysis: Critical threshold versus continuous dose-response relationship

2. Do Genetic Susceptibility, Toll-like Receptors, and Pathogen-associated Molecular Patterns Modulate the Effects of Wear?

3. Macrophages-Key cells in the response to wear debris from joint replacements

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