Identifying binding hot spots on protein surfaces by mixed‐solvent molecular dynamics: HIV‐1 protease as a test case
Author:
Affiliation:
1. Department of Medicinal ChemistryCollege of Pharmacy, University of Michigan428 Church St.Ann Arbor MI48109‐1065
2. Department of BiophysicsCollege of LSA, University of Michigan930 N. University St.Ann Arbor MI48109‐1055
Funder
National Institutes of Health
National Science Foundation
University of Tennessee
Publisher
Wiley
Subject
Organic Chemistry,Biomaterials,Biochemistry,General Medicine,Biophysics
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bip.22742
Reference71 articles.
1. Analysis of the binding surfaces of proteins
2. Use of Amino Acid Composition to Predict Ligand-Binding Sites
3. Identification of the Druggable Concavity in Homology Models Using the PLB Index
4. Studies of protein-protein interfaces: A statistical analysis of the hydrophobic effect
5. An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins
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