In vitrometabolism of specific CYP2D and CYP3A opioid substrates using rat liver S9 fractions and mass spectrometry reveal a severe metabolic impairment with increasing age-Reference-Cited by-同舟云学术

In vitrometabolism of specific CYP2D and CYP3A opioid substrates using rat liver S9 fractions and mass spectrometry reveal a severe metabolic impairment with increasing age

Published:2016-08-23 Issue:2 Volume:31 Page:e3786
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Salmin Sabrin Fuad¹,Giroux Marie-Chantal²,Vachon Pascal²³,Beaudry Francis¹

Affiliation:

1. Groupe de Recherche en Pharmacologie Animal du Québec (GREPAQ), Département de Biomédecine Vétérinaire, Faculté de Médecine Vétérinaire; Université de Montréal; Saint-Hyacinthe Québec Canada

2. Département de Biomédecine Vétérinaire, Faculté de Médecine Vétérinaire; Université de Montréal; Saint-Hyacinthe Québec Canada

3. Ste-Justine Hospital Research Center; Montréal Québec Canada

Funder

National Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

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