Duplication or amplification of chromosome band 11q23, including the unrearrangedMLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of theTP53 gene and to previous therapy with alkylating agents-Reference-Cited by-同舟云学术

Duplication or amplification of chromosome band 11q23, including the unrearrangedMLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of theTP53 gene and to previous therapy with alkylating agents

Published:2001 Issue:1 Volume:31 Page:33-41
ISSN:1045-2257
Container-title:Genes, Chromosomes and Cancer
language:en
Short-container-title:Genes Chromosom. Cancer

Author:

Andersen Mette K.,Christiansen Debes H.,Kirchhoff Maria,Pedersen-Bjergaard Jens

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference38 articles.

1. ACUTE MYELOGENOUS LEUKAEMIA WITH C-MYC AMPLIFICATION AND DOUBLE MINUTE CHROMOSOMES

2. Establishment and characterization of a megakaryoblast cell line with amplification of MLL

3. Clinical and biological characteristics of adult de novo and secondary acute myeloid leukemia with balanced 11q23 chromosomal anomaly or MLL gene rearrangement compared to cases with unbalanced 11q23 anomaly: confirmation of the existence of different entities with 11q23 breakpoint

4. Amplification of the 11q23 region in acute myeloid leukemia

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