Predicting Cytotoxicity and Enzymatic Activity of Diverse Chemicals Using Goldfish Scale Tissue and Topminnow Hepatoma Cell Line‐based Data

Author:

Kahraman Elif Nagihan1,Saçan Melek Türker1ORCID

Affiliation:

1. Ecotoxicology and Chemometrics LaboratoryInstitute of Environmental SciencesBogazici University Besiktas/Istanbul Turkey

Funder

Bogazici University

Publisher

Wiley

Subject

Organic Chemistry,Computer Science Applications,Drug Discovery,Molecular Medicine,Structural Biology

Reference46 articles.

1. F. Pedersen J. de Bruijn S. Munn K. van Leeuwen 2003. Assessment of additional testing needs under REACH-Effects of (Q)SARs risk based testing and voluntary industry initiatives. JRC Report.

2. European Commission. 2006. Regulation (EC) No 1907/2006 of the European Parliament and of theCouncil of 18December 2006 concerning the Registration Evaluation Authorisation and Restriction of Chemicals (REACH) establishing a European Chemicals Agency amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC 93/67/ EEC 93/105/EC and 2000/21/EC.Official J. Eur. Union. L396 : 1–849.

3. Application of Mass Balance Models and the Chemical Activity Concept To Facilitate the Use of in Vitro Toxicity Data for Risk Assessment

4. Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish

5. In vitro cytotoxicity of metals to bluegill (BF-2) cells

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